Abstract

Recombinant molecules, such as nucleic acids or proteins, including antibodies, antigens, cytokines, enzymes, growth factors and hormones are generated by identifying, isolating and transferring the gene of interest from one organism into the plasmid of another/host organism. The controlled creation of novel functional recombinant molecules is essential for a variety of purposes, including food safety, safe environment, and personalized medicine. Recombinant chymosin was the first recombinant enzyme produced to replace native rennet in cheese making. Recombinant antibodies are robust, reliable, sensitive and rapid biosensor-based detectors of food pathogens. As a research study, among the recombinant ovalbumin and recombinant ovalbumin mutant proteins that were designed, developed, tested and studied for their protective efficiency against egg allergy in a mouse model, a double mutant and a triple mutant were effective in completely preventing anaphylaxis. These recombinant ovalbumin mutants are promising molecules for potential use as substitutes for native ovalbumin in food products, as key reference proteins replacing native ovalbumin in laboratories, and as therapeutics against native ovalbumin in medicine. This theoretical discourse presents an overview of recombinant molecules for food safety, improved nutrition, personal wellness, personalized medicine, safe environment, better quality of life, and thereby for a healthy society.