Effects of Negative Emotional-affective States in Health-related Quality of Life in Chronic Health Diseases: Anxiety and Depression in Hematological Cancer, Chronic Renal Failure, and Fibromyalgia

Abstract

Affective and emotional states can affect functioning and Health-related Quality of Life (HRQoL). This negative influence may be greater in chronic diseases and may determine prognosis. We present here the associations between anxiety-depression and HRQoL in patients with hematological cancer, chronic renal failure and chronic pain (fibromyalgia). Measures of anxiety and depression (Hospital Anxiety and Depression Scale, State-Trait Anxiety Inventory, Beck Depression Inventory) and HRQoL (Short-Form Health Survey, SF-36) were taken in 69 patients with hematological cancer (Hodgkin’s and non-Hodgkin’s lymphoma, multiple myeloma and acute myeloid Leukemia), 52 chronic kidney disease patients on hemodialysis and 143 patients with fibromyalgia. Two general functioning indexes were collected from the SF-36, the general physical and mental components, computed using equations weighted for the Spanish population from the eight functional domains of this instrument (physical function, physical role, bodily pain, general health, vitality, social function, emotional role, and mental health) besides the global score. Results showed negative correlations between anxiety-depression and HRQoL in hematological cancer (anxiety: r=-.14, ns, -.35 and -.39; depression: r=-.39, -.35 and -.57; for the physical, mental and overall HRQoL scores, respectively) chronic kidney disease (anxiety: r=-.48, -.73 and -.73; depression: r=-.61, -.63 and -.73; for the physical, mental and overall HRQoL scores, respectively) and fibromyalgia (anxiety: r=-.52, -.34 and -.62; depression: r=-.57, -.37 and -.63; for the physical, mental and overall HRQoL scores, respectively). These results suggest the need to evaluate and treat negative affective states in chronic health diseases in order to improve HRQoL and general wellbeing.

Presenters

Gustavo A Reyes Del Paso
Professor, Psychology, University of Jaén, Spain

Details

Presentation Type

Poster Session

Theme

Health Promotion and Education

KEYWORDS

DEPRESSION, ANXIETY, HEALTH-RELATED QUALITY OF LIFE, HEMATOLOGICAL CANCER, CHRONIC KIDNEY DISEASE, FIBROMYALGIA