Eighth International Conference on Health, Wellness & Society

Abstract

The diabetes and related complications are very problematic for fertility and in a pregnancy for maternal and fetal health. This research is a focus on women in pregnancy, in particulary the attention is about risk factors as obesity, genetic conditions, metabolic diseases. This research is divided into part: first is the lifestyle and diabetes conditions and consequences, in the fertility age and in pregnancy, the second is a educational foetal programming for prevention. The problems are related in 7 cases on 10 to diabetes mellitus in pre-pregnancy. In a cohort study of 92 women, 45 in pregnancy and 47 in pre-conceptional age, only 10% of pregnant women and 3% of non pregnant know their diabetics conditions. In pre-pregnancy the diabet, in association with a bad lifestyle, create a pre-inflammatory conditions with oxidation reactions, dangerous for mitochondrial genomic and for regulation of gene expression in future fetal development. Infact in this study in a women with pre-pregnancy diabetes as new condition, the related complications as hypertension and metabolic scompenses was evident in 15 women, with overweight or obesity too. After this study the screening revealed in 15 cases the diabetes condition and complications with hypertension and hyperglycemia, in particulary the consequence was the influences for fetal nutrition and neurodevelopment. The epigenetic effect of inflammatory status caused a vasoconstriction and damage against tissues in development in particulary neuromuscular structures and renal development. The foetal programming and educational diabetics screening is the purpose for improve the pre-pregnancy health for a future life.