Abstract
Brazilian biodiversity is one of the largest in the world within two global biodiversity hotspots: Atlantic Forest and Cerrado. Brazilian native fruits have been shown to be excellent sources of polyphenols that are associated with multiple biological mechanism and protection against NCD. This study aimed to evaluate the impact of the consumption of the fruits Eugenia brasiliensis Lam (GR), Eugenia involucrata DC (RC) and Eugenia Neomyrtifolia (UV) on the glycemic, insulinemic and postprandial inflammatory responses of healthy individuals. Healthy volunteers (n=15) were enrolled in a crossover placebo-controlled study. Capillary blood samples were collected in fasting and 15, 30, 45, 90 and 120 after the consumption of juice containing 90g of pulp of GR, RC, UV or water, followed by the consumption of a bread containing 25g of available carbohydrate. It was evaluated the biochemical parameters of glucose, insulin and cytokines levels; the action of flavonoid fruit extracts on the alpha-amylases activities. There was a significant reduction in glycemia at times 15 (p=0.009) and 45 minutes (p=0.047) after consumption of GR juice, compared to the control. IL-1B levels statistically increased 2h after the bread consumption (p=0.042) but its levels remain low after the consumption of all the juices with bread consumptions. All extracts had the ability to reduce alpha-amylase activity. GR had the highest value of total phenolics. All the evaluated fruits can be considered a beneficial food in the management of postprandial hyperglycemia and can play a role in modulating inflammation followed by a high glycemic meal.
Presenters
Isabella DuartePostdoctoral Researcher, Department of Food and Experimental Nutrition, University of Sao Paulo (USP), São Paulo, Brazil
Details
Presentation Type
Theme
KEYWORDS
BRAZILIAN BIODIVERSITY, POLYPHENOLS, INSULIN, GLICEMIC INDEX, INFLAMMATION, DIGESTIVE ENZYMES
