Abstract
Polysaccharide-based biopolymer particles are known as biocompatible, sustainable and easy to be modified, and widely used in food and biomedical fields. In this study, a novel polysaccharide-based particle as curcumin (Cur) carrier was developed through self-assembly driven by electrostatic interactions between carboxymethylated corn fiber gum (CMCFG) and chitosan (Cs). Firstly, the chemical structure of synthesized CMCFG was characterized to prove successful carboxymethylation. Then Cur-loaded CMCFG/Cs particles (Cur-CMCsPs) with different mass ratios of CMCFG to Cs (1:3, 1:2, 1:1, 2:1 and 3:1) were prepared and their particle size, zeta-potential, crystalline structure and micro-morphology were determined. Smaller particle size was observed when the mass ratio of CMCFG to Cs exceeded 1:1, among which the lowest hydrodynamic diameter was less than 300 nm, as uniform spherical particles. Furthermore, the highest encapsulation efficiency of the resulting Cur-CMCsPs surpassed 93% and the Cur loaded in particles showed the excellent photo/thermal stability. Besides, the particles could significantly improve the bioaccessibility of Cur reaching 74.94%. This study provides strategy support for suitably designing biopolymer particles as delivery vehicles of hydrophobic nutrients in food and biomedical fields.
Details
Presentation Type
Theme
Food Production and Sustainability
KEYWORDS
Biopolymer particlesCorn fiber gumCarboxymethylationCurcuminElectrostatic interactions
