Abstract
The LuBAIR™ Paradigm is a novel approach to ascribe meaning to behavioral expressions in advanced Neurocognitive Disorders (NCDs) when the reliability of a clinical assessment is limited. The meaning ascribed to each behavioral category was used to identify those who respond to the use of Atypical Antipsychotics (AAPs) in management. De-prescribing attempted on patients who qualified to enter this retrospective study and was defined as successful if individuals were completely withdrawn from AAP and remained off them for 60 days, without the re-emergence of behaviors. The LuBAIR™ Inventory was filled on two occasions. The data collected on the second occasion, in the successful and failed de-prescribed groups, were compared in this retrospective study. MANOVA, Chi Square paired t-test statistical analyses were used to detect the differences in the behavioral categories between the two cohorts.Cohen d was used to measure effect size. Patients who did not have Mis-Identification and Goal-Directed Expressions were more likely to successfully de-prescribe: X2 (1, N = 40) = 29.119 p < 0.0001 and X2 (1, N = 40) = 32.374, p < 0.0001, respectively. Alternatively, the same behavioral categories were more likely present in patients who failed de-prescribing: MANOVA and paired t-test (p < 0.0001). Atypical antipsychotics, in their role as an antipsychotic and mood stabilizer, may be used to manage Mis-Identification and Goal-Directed Expressions, respectively. The use of the LuBAIR™ Inventory and Paradigm may have the potential to predict which behavioral categories associated with advanced NCD may justify the use of AAP in their management.
Presenters
Atul Sunny LuthraPsychiatrist, Medical Coordinator, Program for Older Adults, Homewood Health Centre, Ontario, Canada
Details
Presentation Type
Paper Presentation in a Themed Session
Theme
Medical Perspectives on Aging, Health, Wellness
KEYWORDS
NEUROCOGNITIVE DISORDERS, BEHAVIOR EXPRESSIONS, ATYPICAL ANTIPSYCHOTIC MEDICATIONS, LUBAIR
