Abstract
Human milk is essential in the nutrition of newborns as it provides essential compounds such as lipids, sugars, immunological factors, and growth hormones that confer multiple health benefits. It contains a great diversity of microorganisms, including several species of the genera Lactobacillus, Bifidobacterium, Streptococcus, or Staphylococcus. These microorganisms are transmitted to the newborn during lactation and will be an important part of the establishment of its microbiota. The intestinal microbiota is a factor that influences human health, thus, a dysbiosis in it has been associated with the development of different diseases, such as allergies, asthma, diabetes, obesity, metabolic syndrome, necrotizing enterocolitis, or diarrhea. Despite the biomedical and biotechnological relevance of microorganisms in human milk, the study, analysis, and application are limited to the possibility of being cultured in the laboratory. However, thanks to advances in massive next-generation sequencing technologies and molecular techniques, an understanding of their taxonomic structure and functional role in infant health has begun to emerge. Considering the importance of microbiological communities in human milk for newborns, in this project we performed a meta-taxonomic analysis by amplification of ribosomal markers in a group of mothers with different diseases, such as hypertension, obesity, and diabetes, as well as abuse of legal and illegal substances, to explore the ecological dynamics of microbiological communities related to altered health status.
Presenters
Mario Ivan Aleman DuarteBiotechnology, University of Guadalajara, Mexico Edgar Balcázar López
Universidad de Guadalajara Jessica Guadalupe Solís Aguilar
Médico Pasante, Universidad de Guadalajara Jesus Alonso Amezcua López
Universidad de Guadalajara Blanca Rosa Aguilar Uscanga
Research Professor, Pharmacobiology, Centro Universitario de Ciencias Exactas e Ingenierías de la Universidad de Guadalajara, Jalisco, Mexico Josué Raymundo Solís Pacheco
Profesor, Pharmacobiology, Universidad de Guadadalajara, Mexico
Details
Presentation Type
Paper Presentation in a Themed Session
Theme
Interdisciplinary Health Sciences
KEYWORDS
DIVERSITY, NONCOMMUNICABLE DISEASES, METAGENOMICS, MICROBIOTA, HUMAN MILK
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