The Microfluidic Nanotechnology Generates Knowledge to Benefit Cancer Patients : Microfluidic Single Cell Assay Generates Multidrug Resistance Knowledge

Abstract

We have employed the biochip to conduct single cell analysis for cancer research. The analysis is enhanced by the knowledge of microfluidics and nanotechnology to measure cancer cells. The epistemology in science and medicine generates the data and metadata of multidrug resistance (MDR) in cancer cells of patients. MDR, which is one of the major obstacles in drug delivery in cancer treatment, may be overcome by using MDR inhibitors, thus facilitating treatment and benefiting cancer patients in the society. The data and metadata of MDR assist doctors and clinicians as the knowledge end-users to make informed clinical decisions. The data also benefit drug discovery of pharmaceutical end-users and assist in patient selection for clinical drug trials. The boundaries, limitations, strengths, functions and ownership of knowledge of the MDR data are also discussed.

Presenters

Paul Chi Hang Li
Professor, Chemistry, Simon Fraser University, British Columbia, Canada

Details

Presentation Type

Paper Presentation in a Themed Session

Theme

Knowledge Makers

KEYWORDS

Biochip, Cancer, Microfluidics, Nanotechnology, Science, Medicine, Multidrug resistance, Drug Delivery