Intervention with Golden Berry Fruit (Physalis peruviana L.): Confirming Its Impact on Insulin-Associated Signaling Pathways

Abstract

The objective of the research was to identify the changes in plasma metabolites that can occur after ingestion of cape gooseberry in a group of healthy people. The results show that, after the daily intake of 150 g of cape gooseberry for 19 days (medium-term intervention), the level of Superoxide Dismutase (SOD) increases, a very powerful endogenous antioxidant enzyme of the human body that reduces the set of free radicals that can produce oxidative damage (Reactive Oxygen Species - ROS). This indicates a better functioning of the antioxidant defense system, generating a decrease in the damage of all cells. After the consumption of 250 g of cape gooseberry 6 hours after ingestion (acute intervention), an increase in the level of Superoxide Dismutase (SOD) and significant improvements in the metabolism of insulin signaling are evidenced. It is precisely where the role of cape gooseberry stands out, improving the ability of cells to respond to insulin, due to the improvement in it signaling, controlling critical energy functions such as glucose and lipid metabolism, and avoiding resistance. to insulin. This resistance is one of the main manifestations associated with Type 2 Diabetes Mellitus (DM2). This shows the importance of cape gooseberry consumption in maintaining the insulin signaling pathway, useful in the prevention of T2 diabetes mellitus.

Presenters

Alberto Angel-Martín
Professor, Escuela de Nutrición y Dietética , Universidad Industrial de Santander, Santander, Colombia

Details

Presentation Type

Paper Presentation in a Themed Session

Theme

Food, Nutrition, and Health

KEYWORDS

METABOLOMIC, PHYSALIS PERUVIANA, NUTRITIONAL INTERVENTION, INSULIN