Abstract
The intersection of cancer genomics with novel immunotherapies is revolutionizing patient care. The number of mutations found in tumors has been associated with overall survival of lung cancer patients treated with immunotherapy. Inspired by these findings, we used clinical and genomic data from a lung cancer patient cohort to build a 3D information visualization and illustrate this association. Certain demographics and patient characteristics are incorporated in this installation project that shows patients’ overall survival (y-axis) versus the number of mutations (x- and z-axis). Multiple materials were used to represent patients and their characteristics. First, patients are represented by wire balls that are color-coded based on the smoking status (black for current or former smokers and blue for non-smokers). Second, two blocks at the top of each wire ball represent race (yellow for Asians, black for African Americans, and white for Caucasians) and gender (purple for Females and light blue for Males). Third, a blue wire cover represents patient’s overall survival, a black wire cover signifies a death event, and a white wire cover indicates that the patient was still alive when data was collected. This installation work visually supports the notion that a high number of mutations may confer a survival benefit for lung cancer patients treated with immunotherapy. We are envisioning that this work may catalyze a communication channel between patients and researchers.
Presenters
Taxiarchis BotsisAssistant Professor, Oncology, Johns Hopkins University School of Medicine, Maryland, United States Valsamo Anagnostou
Assistant Professor, Thoracic Oncology, Johns Hopkins Cancer Center, Maryland, United States
Details
Presentation Type
Paper Presentation in a Themed Session
Theme
New Media, Technology and the Arts
KEYWORDS
INFORMATION VISUALIZATION, ARTS IN MEDICINE, IMMUNOTHERAPY
