Cell Division and Cancer

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Abstract

This unit will include reading materials, videos, activities and students created projects over the topics of cell division in eukaryotic cells, how the cell cycle works, and what role it plays in producing or preventing the growth of cancer cells. The following IB understandings (U), applicatoins (A) and skills (S) will be covered and students will be expected and assessed on these specific standards: 3.2.U3: Eukaryotic chromosomes are linear DNA molecules associated with histone proteins (Oxford Biology Course Companion page 151). 1.6.U2: Chromosomes condense by supercoiling during mitosis (Oxford Biology Course Companion page 52). 7.1.U2: Nucleosomes help to supercoil the DNA (Oxford Biology Course Companion page 347). 7.1.S2: Utilization of molecular visualization software to analyze the association between protein and DNA within a nucleosome (Oxford Biology Course Companion page 348). 1.6.U4: Interphase is a very active phase of the cell cycle with many processes occurring in the nucleus and cytoplasm (Oxford Biology Course Companion page 52). 1.6.U1: Mitosis is division of the nucleus into two genetically identical daughter nuclei (Oxford Biology Course Companion page 51). 1.6.S1: Identification of phases of mitosis in cells viewed with a microscope or in a micrograph (Oxford Biology Course Companion page 52). 1.6.S2: Determination of a mitotic index from a micrograph (Oxford Biology Course Companion page 55). ​1.6.U3: Cytokinesis occurs after mitosis and is different in plants and animal cells (Oxford Biology Course Companion page 55). 1.6.U5: Cyclins are involved in the control of the cell cycle (Oxford Biology Course Companion page 56). 1.6.NOS: Serendipity and scientific discoveries- the discoveries of cyclins was accidental (Oxford Biology Course Companion page 56). 1.6.U6: Mutagens, oncogenes and metastasis are involved in the development of primary and secondary tumours (Oxford Biology Course Companion page 57). 1.6.A1: The correlation between smoking and incidence of cancers (Oxford Biology Course Companion page 57). 6.4.A2: Causes and consequences of lung cancer (Oxford Biology Course Companion page 316). 6.4.NOS: Obtain evidence for theories- epidemiological studies have contributed to our understanding of the causes of the lung cancer (Oxford Biology Course Companion page 316).